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Retinoblastoma is the most frequent intraocular tumor in childhood. The definitive treatment is enucleation. The management of the anophthalmic socket consists in the use of a plastic implant. The problem is that they are expensive and they usually extrude. The use of dermal-fat grafts minimizes the hemi-facial hypoplasia. They usually grow with the face, and help to expand the orbital bones, thus...
The case involves a 35-year-old man, with a history of retinitis pigmentosa, who presented with a bilateral cystoid macular edema associated with bilateral epiretinal membrane, which was resistant to treatment with oral acetazolamide and intravitreal bevacizumab. The treatment with oral eplerenone was able to improve the visual acuity and macular thickness of this patient.A variety of treatments have...
To describe the ultrasound, histopathological and genetic characteristics of uveal melanoma in a Mexican-Mestizo population.A total of 39 enucleated eyes with a histopathological diagnosis of uveal melanoma were assessed by describing the clinical findings, and ultrasound, histopathological and genetic features.A high correlation was observed between tumor height measurement using ultrasound and histopathology...
Three clinical cases are presented of MEK retinopathy associated with the combination of cobimetinib and vemurafenib characterized by alteration of the retinal pigment epithelium and neurosensory detachment. Two of the cases conserved the vision of the unit, and the third developed a large bilateral neurosensory detachment with final visual acuity of 0.6 for the right eye and 0.1 for the left one...
Two cases of tubulointerstitial nephritis and uveitis are presented. Immunosuppressive therapy was required to control the uveitis. Contrary to that usually described, uveitis became chronic, which made immunosuppressive therapy necessary. Nephritis was successfully treated with steroids.Tubulointerstitial nephritis and uveitis syndrome is an under-diagnosed disorder and requires clinical suspicion...
The case is presented of a 73-year-old male patient who referred to having black and white vision. Computed tomography showed normal pressure hydrocephalus (NPH). Magnetic resonance imaging was not performed because the patient refused to undergo further examinations.Achromatopsia may be the first or only NPH symptom. It may be prudent to ask patients with NPH regarding colour vision.
The purpose of the present study is to review the frequency of intraocular metastases as first presentation of systemic disease, and to identify clinical and tumour characteristics.Retrospective study of consecutive cases diagnosed of intraocular metastasis at a referral intraocular tumours unit between 1993 and 2014. General, epidemiological and ophthalmological characteristics were recorded.A total...
Geographic atrophy is characterized by severe visual deficit whose etiology and pathophysiology are yet to be elucidated. As a working hypothesis, oxidative damage could trigger a chronic inflammation in Bruch's membrane–RPE–choriocapillaris complex, mostly due to complement pathway overactivation. Some individuals with mutations in the complement system and other factors have diminished capacity...
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